Dr. Frank Santopietro has spent 50 years asking the same question: why is this person in pain, and what's actually causing it? That curiosity — and a patented orthotic system — has helped thousands of patients get back to the lives they love.
Dr. Frank Santopietro established his podiatry practice in Brookline in 1974. Over five decades, he has developed a deep expertise in sports medicine, biomechanics, and custom orthotic fabrication, including his own patented EvenKeel Orthotic System.
For 25 years — from 1982 to 2007 — Dr. Santopietro served as team podiatrist for the New England Patriots. He has also cared for collegiate athletes at Providence College, Boston College, and Boston University, and has consulted for NFL teams including the Tennessee Titans and the St. Louis (now Los Angeles) Rams.
His philosophy is rooted in conservative care: understanding the whole patient, exhausting non-surgical options first, and building solutions that last. That approach has earned him the trust of thousands of patients, from weekend warriors to pediatric patients and everyone in between.
EvenKeel is a family practice in every sense. In 2004, Frank's son David joined the practice and began building the technology infrastructure behind it — co-inventing the patented orthotic system and designing the manufacturing process that delivers it. Frank's wife Mary Lou has managed the office since the mid-1990s, and Nadine Eisenhauer has been part of the team since 2005. Together, they have spent decades making sure patients feel known, not just treated.
📄 Download: Injuries in the Young Athlete — a paper written by Dr. Santopietro for parents and coaches
Walk Pain-Free
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All Ages Welcome
From sports injury recovery to long-term orthotic support, we offer a full spectrum of foot and ankle care, always beginning with the most conservative approach.
Dr. Santopietro's patented EvenKeel Orthotic System is precision-crafted for each patient to correct the biomechanical issues that cause chronic pain.
Learn more →Specialized treatment for runners, cyclists, and athletes of all levels. We address acute injuries and recurring pain patterns to keep you performing at your best.
Book a visit →When surgery is the right path, we connect you with trusted surgical specialists in our network, ensuring continuity of care and a warm handoff, not a dead end.
Talk to us first →Comprehensive monitoring and wound care for diabetic patients, with a focus on prevention, early intervention, and maintaining long-term foot health.
Schedule care →Early intervention for flat feet, in-toeing, heel pain (Sever's disease), and other childhood foot conditions to build healthy foundations for life.
Book for your child →Detailed gait analysis and biomechanical assessment to identify the root causes of recurring foot, knee, hip, and back pain. Not just the symptoms.
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Our approach is systematic, patient-centered, and built around long-term outcomes. No quick fixes.
We listen carefully to your history, symptoms, and goals. Understanding you is step one.
A thorough biomechanical evaluation: gait analysis, structural assessment, and imaging when needed.
A personalized plan starting with the most conservative options first. Custom orthotics, physical therapy guidance, or targeted intervention.
Ongoing monitoring and adjustment. We're invested in your long-term outcome, not just the next appointment.
Dr. Santopietro's patented EvenKeel Orthotic System was decades in the making. It's a precisely engineered solution that addresses the biomechanical root causes of foot and body pain.
The only orthotic system of its kind, developed and refined over 50 years of clinical practice and patient outcomes.
Every orthotic is built from a photo analysis of your feet and a gait video, using proprietary technology we developed to capture exactly what each patient needs.
Correcting foot mechanics can resolve pain in the knees, hips, and lower back, not just the feet.
Designed to work in everyday shoes, athletic footwear, and specialized gear. Supportive, without limiting your lifestyle.
"Dr. Santopietro's skills honestly changed my youngest son's life. His expertise made many physical things possible for Kyle that would not have been otherwise — opportunities that brought him happiness and real confidence."
"Over the years, Dr. Santopietro's treatment has spared me from pain pills, cortisone injections, and even surgery. I had a partially torn Achilles — he managed it brilliantly. I've been running better ever since."
"What a sigh of relief when he told me that he always uses conservative methods before resorting to surgery. I left feeling heard and cared for."
"I had explored various options to alleviate the pain in my left foot, but none proved effective. Within just three months of following Dr. Santopietro's advice, I was able to resume walking without any pain. Fast forward a year — zero foot pain and nothing but contentment with my newfound comfort."
"Frank Santopietro has been making the perfect orthotics for my strangely shaped feet for a number of years and his inserts have made a wonderful difference in the way I walk. I am more stable and comfortable than before. I recommend him and his staff without reservation."
"I thought I could never play volleyball or walk pain free again. I could not believe the difference his orthotics made — immediately I could bend my knee normally again. I now own 4 pairs for walking shoes, home shoes, indoor volleyball, and outdoor volleyball. A true lifesaver."
"My gait used to be strained and now I can walk, run, and hike correctly thanks to his orthotics. It sounds like some people disagree with his treatment plan — but if you are not committed to following through, he is not the doctor for you. I have found that he is very knowledgeable and does his best to help each patient."
"Dr. Santopietro and his staff are friendly and engaging. My 85-year-old mom with RA and I have visited three times to fit and pick up her orthotics. What a blessing! Mom is stabilized and walking so much better — I am booking appointments for myself and my dad!"
"I literally would not be walking without pain if it weren't for his amazing orthotics and careful attention to adjustments. Mary Lou, his wife, makes you feel like you just came home. Nadine rounds out the team with precision and a friendly manner. I've seen him for 10 years after a rock climbing accident that left me largely unable to walk for almost 3 years."
"I went to Dr. Santopietro after years of trying over-the-counter orthotics and having hip problems exacerbated by foot problems. His expertise is unmatched. His orthotics have made a huge difference in a short time and my hip feels better than ever."
"Dr. Santopietro really spends the time with you. I had foot and heel pain for almost half a year before it got too painful to ignore. After a couple of weeks the pain has immensely gone away. The orthotics cost a little bit of money but it's worth it knowing how much better I feel."
"I have been going to see Dr. Santopietro for over 30 years. He really confronted head-on the mechanical issues underlying my problems. If you want a sensible, competent, caring podiatrist, this is the guy."
Call us at 617.734.0003 or request an appointment online. We'll confirm quickly and get you seen soon.